- Potassium (K+ ): Even small changes in extracellular K+ concentration will have significant effects on the transmem brane potential gradient, and thereby the function of neuromuscular and cardiac tissues.
- Sodium (Na+): As the most abundant extracellular fluid solute, Na+ is the major determinant of its osmolality and thereby the principal determinant of water distribution between the intracellular and extracellular compartments. This highlights the role of Na+ in the maintenance of blood volume and thereby blood pressure.
- Chloride (Cl- ): As the second most abundant extracellular fluid ion after Na+, and the most abundant extracellular fluid anion, Cl– is essential for the maintenance of normal plasma osmolarity.
- Ionized Calcium (iCa2+): The maintenance of iCa2+ within normal limits is not only important for the structural integrity of bones but for a range of physiological functions, including: hemostasis, cardiac and skeletal muscle cell contraction, neuromuscular transmission and action of many hormones (calcium-signaling).
- Ionized magnesium (iMg2+): iMg2+ relates to the stabilization of intracellular potassium, which ensures the normal functionality of myocardium, nerve and muscle.
Accuracy Comparison
The accuracy of Eaglenos Electrolyte Analyzer has been validated by comparing with the wet chemistry blood gas biochemical analyzer(using 136 sets of samples). The linear regression analysis shows a strong positive, linear relationship between the results of the two analyzers (R2 > 0.94 for all parameters), demon strating the accuracy of our analyzer for testing K+, Na+, Cl-, iCa2+ and iMg2+ concentration.
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